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public:volunteer_blindnessnos

Sighted participants

Eligibility Criteria:

  • Normal vision and hearing
  • Normal neurologic history
  • Between the ages of 40 and 65
  • No metal implants in your body, no cardiac pacemakers, claustrophobia, or other contraindication to MRI scanning

Total participation is about 2 hours, and includes:

  • A 1 hr MRI scan, part of which involves listening to sentences through headphones and pressing buttons in response
  • Collection of a saliva sample for genotyping (identification of gene type)
  • A 5-minute test of visual perception
  • A brief ophthalmologic and medical history to determine eligibilty
  • Signing and review of consent and demographic forms

Compensation:

  • 60 dollars
  • Travel expenses
  • A picture of your brain

Location: Hospital of the University of Pennsylvania, 3400 Spruce St. Philadelphia, PA 19104

Contact: Sarah Daina, Research Assistant

Phone: (215) 804-9129

E-mail: GKAguirreLab@gmail.com

Facebook: Aguirre Lab

Visually impaired participants

Eligibility Criteria:

  • Blindness or severe vision loss in both eyes of any duration
  • Normal hearing and neurologic history
  • At least 18 years old
  • No metal implants in your body, no cardiac pacemakers, claustrophobia, or other contraindication to MRI scanning

Total participation is about 2 hours, and includes:

  • A 1 hr MRI scan, part of which involves listening to sentences through headphones and pressing buttons in response
  • Collection of a saliva sample for genotyping (identification of gene type)
  • A 5-minute test of visual perception
  • A brief ophthalmologic and medical history to determine eligibilty
  • Signing and review of consent and demographic forms

Compensation:

  • 60 dollars
  • Travel expenses
  • A picture of your brain

Location: Hospital of the University of Pennsylvania, 3400 Spruce St. Philadelphia, PA 19104

Contact: Sarah Daina, Research Assistant

Phone: (215)804-9129

E-mail: GKAguirreLab@gmail.com

Facebook: Aguirre Lab

About the study

We know from hundreds of years of research that the experience of blindness alters the structure and function of the brain. This has always been of scientific interest, but increasingly these changes have clinical relevance, as treatments for blindness in adulthood are in active development.

We use painless, non-invasive MRI scanning to study these brain alterations in blind volunteers. The ideal subject has severe and nearly equal vision loss in both eyes; so severe as to require alternative approaches or technologies to assist navigation and reading. We are interested in studying people who lost their vision early in life or more recently.

The experience of being in the study is much like a regular MRI scan, except that during our study the volunteer also hears some sounds and perhaps be shown some flashing lights. The entire study takes a few hours, including the time to complete paperwork, perform a simple vision test, provide a sample of saliva for genetic analysis, and finally conduct the MRI scan.

There are no known harmful effects of MRI scanning itself. Sometimes people become claustrophobic, and there are a few medical conditions—related to having metal in the body-which are contraindications for participation. If you are interested in participating, we would run through a list of these possible medical conditions to make sure that you qualify for the study.

We pay for transportation to the Hospital of the University of Pennsylvania, lunch during the day, and $60 an hour for your time.

/home/aguirreg/html/wiki/data/pages/public/volunteer_blindnessnos.txt · Last modified: 2013/03/13 14:37 by aguirreg